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ALDO KETO REDUCTASE FAMILY 1 MEMBER C3
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DeCS
Descriptor
English
:
Aldo-Keto Reductase Family 1 Member C3
Descriptor
Spanish
:
Miembro C3 de la Familia 1 de las Aldo-Ceto Reductasas
Descriptor
Portuguese
:
Membro C3 da Família 1 de alfa-Ceto Redutase
Synonyms
English
:
17-beta-Hydroxysteroid Dehydrogenase Type 5
AKR1C3 Protein
Dihydrodiol Dehydrogenase 3
17 beta Hydroxysteroid Dehydrogenase Type 5
Aldo Keto Reductase Family 1 Member C3
Tree Number:
D08.811.682.047.150.700.156.875
D08.811.682.047.436.375.140
D08.811.682.047.820.284.937
D08.811.682.047.820.375.500
Definition
English
:
Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of
PROSTAGLANDIN D2
and
PROSTAGLANDIN H2
, as well as the
oxidation
of 9alpha,11beta-PGF2 to
prostaglandin D2
. It can also interconvert
estrogens
,
ANDROGENS
; and
PROGESTINS
between their active forms and inactive metabolites.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57018
Unique Identifier:
D000074425
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS